Structures of an all-α protein running along the DNA major groove
نویسندگان
چکیده
منابع مشابه
A peptide interaction in the major groove of RNA resembles protein interactions in the minor groove of DNA.
A 17-amino acid arginine-rich peptide from the bovine immunodeficiency virus Tat protein has been shown to bind with high affinity and specificity to bovine immunodeficiency virus transactivation response element (TAR) RNA, making contacts in the RNA major groove near a bulge. We show that, as in other peptide-RNA complexes, arginine and threonine side chains make important contributions to bin...
متن کاملA dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.
Contact sites of AraC protein to the regulatory site araI of the Escherichia coli araBAD operon have been determined by the chemical-interference technique. DNA fragments were chemically modified an average of once per molecule, and fragments that no longer bound AraC were separated by gel electrophoresis from the DNA fragments still able to bind the protein. The contact sites were then determi...
متن کاملthe major groove of RNA resembles protein interactions in the minor groove ofDNA
A 17-amino acid arginine-rich peptide from the bovine immunodeficiency virus Tat protein has been shown to bind with high affinity and specificity to bovine immunodeficiency virus transactivation response element (TAR) RNA, making contacts in the RNA major groove near a bulge. We show that, as in other peptide-RNA complexes, arginine and threonine side chains make important contributions to bin...
متن کاملProtein–RNA interactions: Getting into the major groove
RNA–protein interactions are involved in many cellular processes, including information storage and transfer, catalysis and transcriptional activation. Our structural knowledge of these interactions at atomic resolution is based on X-ray crystallographic and nuclear magnetic resonance (NMR) studies (for a review see [1]). The crystal structures of a number of RNA–protein complexes have been rep...
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this study examines the effetivenss of task-based activities in helping students learn english language structures for a better communication. initially, a michigan test was administered to the two groups of 52 students majoring in english at the allameh ghotb -e- ravandi university to ensure their homogeneity. the students scores on the grammar part of this test were also regarded as their pre...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2016
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkw133